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From: The endocrine and epigenetic impact of persistent cow milk consumption on prostate carcinogenesis
Figure 2. (A) Synopsis of PI3K-AKT-mTORC1 signaling pathways activated in prostate cancer (PCa) cells. (B) Superimposed nutrigenomic effects of milk signaling. Milk-induced and milk-derived hormones (insulin, GH, IGF-1, MFG-E8, and estrogens) activate PI3K and AKT, which in turn activate mTORC1.
