fig4

Figure 4. Patient #46 (8.8 years) with severe ABCA4-IRD with macular and widespread peripheral atrophy. (A) FAF: centrally reduced intensity in an oval area as well as fleck-like variable intensity with only partial peripapillary sparing. (B) NIA: severely reduced intensity at the posterior pole and slightly less distinct beyond the vascular arcades. (C) W-OCT: severe irregularities of the outer retinal layers with few flecks of subretinal material.