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![Large-scale genomic data-mining implicates dysregulated nuclear receptor-mediated signaling in mental illness](https://image.oaes.cc/a886e836-34f7-4450-9bad-4f8d30103879/4077.fig.4.jpg)
Figure 4. Expression of NR and NR coregulator encoding genes across 16 brain structures and four developmental stages. Row annotations include: NTC subtype (NR/NR coregulator) and genes in GWAS/WES/MWAS loci. Genes fall in eight major clusters defined by most abundant expression in: (1) cerebellum; (2) adults; (3) puberty and adulthood; (4) striatum; (5) prenatally and in childhood; (6) childhood; (7) prenatally; and (8) prenatally and puberty. A1C: Primary auditory cortex; AMY: amygdala; CBC: cerebellar cortex; DFC: dorsolateral prefrontal cortex; HIP: hippocampus; ITC: inferolateral temporal cortex; M1C: primary motor cortex; MD: mediodorsal nucleus of thalamus; MFC: anterior cingulate cortex; OFC: orbital frontal cortex; S1C: primary somatosensory cortex; STC: posterior superior temporal cortex; STR: striatum; V1C: primary visual cortex; VFC: ventrolateral prefrontal cortex.