fig4

Figure 4. Clustal Omega alignment of filamin C protein sequences (3rd line and below) (residues 1500 to 1559) among phylogenetically diverse organisms, and aligned to human filamin A and filamin B (first two lines). The red box shows that the glycine at residue 1546 is completely conserved among species and in the human protein family. NCBI accession numbers are on the left, with species indicator. FICAL is flycatcher bird; PANTR is Pan troglodytes (chimpanzee); CANLF is Canis familiaris (dog). Asterisks below the residue indicate complete conservation. Colons below the residue indicate differences when compared with human filamin A and/or B