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From: Aging triggers mitochondrial, endoplasmic reticulum, and metabolic stress responses in the heart

Figure 4. Aging induces selective endoplasmic reticulum stress response in the heart. (A) Relative mRNA expression levels of ER stress response factors in aged (25-month) vs. young (10-month) CBA/CaJ mice hearts, normalized to Gapdh. (B) Relative mRNA expression levels of ER stress response factors in aged (25- month) vs. young (10-month) CBA/CaJ mice hearts, normalized to Gapdh. Relative expression values were represented as mean ± SEM (n = 3-10). *P < 0.05, **P < 0.01 are considered significant, calculated by an unpaired Student’s t-test using GraphPad Prism software.