fig3
From: Aging triggers mitochondrial, endoplasmic reticulum, and metabolic stress responses in the heart
Figure 3. Impaired metabolic and autophagy regulation in cardiac aging. (A) Reduced mRNA expression levels of autophagy regulators in aged (25-month) vs. young (10-month) CBA/CaJ mice hearts, normalized to Gapdh. (B) Top relative mRNA expression levels of essential metabolic regulators (Mtor, Nrf1, and Prkaa1) in aged (25- month) vs. young (10-month) CBA/CaJ mice hearts, normalized to Gapdh. Relative expression values were represented as mean ± SEM (n = 3-10). Significant difference was calculated by an unpaired Student’s t-test using GraphPad Prism software.
