fig3

The role of senescence in cancer therapy-associated cardiovascular toxicity

Figure 3. Senotherapeutics for targeting cardiovascular senescence. The circular figure presents senolytics, which induce apoptosis specifically in senescent cells by targeting several survival pathways, and senomorphics, which prevent the development of the SASP, restoring the cell to a less agitated state. The molecules affected by each drug are presented in the figure and indicate the pathways that are targeted in senescent cells. Created with BioRender.com software.

The Journal of Cardiovascular Aging

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Portico

All published articles are preserved here permanently:

https://www.portico.org/publishers/oae/