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![The role of brown adipose tissue in mediating healthful longevity](https://image.oaes.cc/24cf7b3b-39d6-40f5-b965-ff7d44968efd/jca4001.fig.2.jpg)
Figure 2. Mechanisms Promoting Healthful Aging By BAT. BAT leads to healthful aging by promoting thermogenesis, energy expenditure, insulin sensitivity, glucose uptake, oxidative stress resistance, mitochondrial function, and blood flow/angiogenesis. This results in protection against obesity, diabetes, exercise intolerance, cardiovascular disease, cancer, and Alzheimer’s disease.