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Figure 5. Prevention of stress-induced ventricular tachycardia in R176Q/+ mice at 12 months after AAV9. (A) Representative surface ECG (top) and intracardiac ventricular (V) lead (bottom) during programmed electrical stimulation (middle part of tracing). (B) Incidence of ventricular tachycardia induction in WT (n = 6 mice), RQ control (Con) (n = 7 mice), and RQ gRNA-SaCas9 (n = 5 mice) groups. The Fisher exact test was performed to compare for differences in arrhythmia induction (B).