fig3

Figure 3. Nobiletin rescues mitochondrial oxygen consumption rate (OCR) and cardiac cell death during hypoxia. (A) mitochondrial OCR in cardiac myocytes under normoxia (NMX) and hypoxia (HPX) in the presence and absence of Nob. (B) Cell viability assessed with vital dyes calcein-AM (green; live cells) and ethidium-homodimer-1 (red; dead cells), bar: 100 μm. Data are expressed as mean ± SEM. **P < 0.01, n = 3-4 independent myocyte isolations, counting > 200 cells for each condition tested.