fig5

Figure 5. Left atrial remodeling and dysfunction in mTAC model. (A) Representative long-axis echocardiography data of sham (left panel) and mTAC mice (right panel) showing the aorta (Ao), and left atrium (LA). (B) Average value of LA size in sham (black dots, n = 6) and mTAC mice (red dots, n = 7). (C) Representative Doppler traces of mitral valve blood flow velocity showing early (E) and atrial (A) waves in sham (left panel) and mTAC mice (right panel). (D) Average of mitral early to atrial waves (E/A) ratio in sham (black dots, n = 6) and mTAC (red dots, n = 7). Data shown mean ± SEM. **P < 0.01 using student’s t-test.