fig2
Figure 2. Effectiveness of aortic constriction in the mTAC model. (A) Representative echocardiography images of the aortic arch in sham (left panel) and mTAC (right panel) mice, showing the constriction (red arrow) of the aorta (Ao). (B) Schematic illustration of the aortic arch and representative recording of blood flow in right carotid (RC; upper panels) and left carotid (LC; bottom panels) from sham (left) and mTAC (right) mice. (C) Quantification of RC/LC ratios in sham (n = 6) versus mTAC (n = 8) mice. Data shown mean ± SEM.