fig4
Figure 4. Myocardial structural remodeling impairs mitochondrial energetic supply and demand. ROS: Reactive oxygen species; HIF-1: hypoxia-inducible factor 1; OXPHOS: oxidative phosphorylation; TCA: tricarboxylic acid; PGC-1α: peroxisome proliferator-activated receptor γ co-activators 1α; PKB: protein kinase B. See Section “CARDIAC REMODELING ALTERS MITOCHONDRIAL BIOENERGETICS” for further details.
