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![Metabolic targets in cardiac aging and rejuvenation](https://image.oaes.cc/0a0eb27d-0961-4326-aaa7-feab5abf5ca4/5155.fig.1.jpg)
Figure 1. Metabolic pathways and regulators affect the hallmarks of aging in the heart. Cx43: Connexin-43; ROS: reactive oxygen species; SASP: senescence-associated secretory phenotype; EPCs: endothelial progenitor cells; AMPK: AMP-activated protein kinase.