fig7

Figure 7. Effects of suppression of the cWNT pathway on myocardial apoptosis. (A) Thin myocardial sections showing apoptosis as detected by the TUNEL assay in the experimental groups. (B) Quantitative data on the number of cells stained positive for the TUNEL assay in the experimental groups (N = 6-7). (C) Quantitative RT-PCR data showing transcript levels of genes involved in apoptosis in the experimental groups (N = 5-7). RT-PCR: Reverse transcription-polymerase chain reaction; Bax: BCL2 associated X; Bcl2: B-cell lymphoma 2; Lrp1: low-desntiy lipoprotein receptor related 1; Bicc1: BicC family RNA binding protein 1; Bok: BCL2-related ovarian killer; Bak: BCL2-antagonist/killer 1; Bid: BH3 interacting domain death agonist; Bad: BCL2-associated agonist of cell death; Casp8: caspase 8; Puma (also known as BBC3): BCL2 binding component 3. P_G: P value for the effect of the genotype; P_Tr: P value for the effect of treatment; P_i: P value for treatment-by-genotype interaction.