fig1

Secretome and extracellular vesicle signatures in bone marrow-derived mesenchymal stromal cells after expansion in standard and next-generation media

Figure 1. BMSCs phenotype in analyzed media. (A) BMSCs showed fibroblast-like morphology with a more elongated shape in P and S/X conditions. Scale bar = 10 µm; (B) Violin plots of BMSCs density, N = 8 donors. Median and quartiles are shown as dashed and dotted lines, respectively; (C) Violin plots of BMSCs viability, N = 8 donors; (D) Violin plots showing the size distribution of BMSCs in suspension after trypsin detachment and before secretome production, N = 8 donors. Median and quartiles are shown as dashed and dotted lines, respectively. BMSCs: Bone marrow-derived mesenchymal stromal cells; F: fetal bovine serum; P: platelet lysate; S/X: serum/xeno free.

Extracellular Vesicles and Circulating Nucleic Acids
ISSN 2767-6641 (Online)
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