fig3

Figure 3. ^*Significant differences from control subjects (healthy controls) (P < 0.05). Each ligand’s measured value is normalized to the value of CD63. The columns represent healthy controls (blue), patients with T2DM (orange), and patients with HT (gray). (A) Antigens with high expression on the surface of any of the EVs. Antigens with (B) middle and (C) low expression on the surface of EVs. Values are shown as the mean ± SD. T2DM: Type II diabetes mellitus; HT: hypertension; Evs: extracellular vesicles.