fig8
Figure 8. Exosomes and ASC therapy prolong the survival of skin grafts. (A) Skin allograft appearance of Exosomes + model, ASCs + model, and control mice from day 7 to 25 post-transplantation; (B) The graft survival rate in Exosomes + model, ASCs + model, and control mice within 25 days post-transplantation (n = 8); (C) Flow cytometry gating strategy for PD-1+Treg subsets; (D) Changes in the proportions of PD-1+Tregs in the spleen in models treated with PBS, 0.5 × 108 Exosomes, 1 × 108 Exosomes, 1.5 × 108 Exosomes, and ASCs. ASCs: Adipose-derived stem cells. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
