fig3

Figure 3. Characteristics of EVs from L. rhamnosus PCM 489. (A) NTA-based particle size distribution analysis; a representative histogram of the average size distribution from three measurements of a single sample (black line) is presented. The presented blue numbers indicate the maxima of peaks, and the red areas show the SD between measurements. The size parameters of EVs are included. Factors D10, D50, and D90 denote that 10%, 50%, and 90% of the EV population had a diameter of less than or equal to the presented value; (B) TEM images of LrEVs. White arrows point to the individual particles. Scale bars included in individual panels. EVs: Extracellular vesicles; NTA: nanoparticle tracking analysis; TEM: transmission electron microscopy; SD: standard deviation.