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![Transcriptomic analysis of plasma-derived small extracellular vesicles reveals the pathological characteristics of normal tension glaucoma](https://image.oaes.cc/7295583d-d335-41bc-be33-d604eb2e9cbb/evcna5045.fig.6.jpg)
Figure 6. The plasma sEVs let-7b-5p level is a significant diagnostic factor in severe NTG patients. (A) According to the MD value, we stratified the NTG patients into two groups. The relative expression levels of let-7b-5p in the two groups. Data are represented as the mean ± SEM; (B) ROC curve analysis was performed to analyze the ability of let-7b-5p in terms of evaluating the severity of NTG. sEVs: Small extracellular vesicles; NTG: normal tension glaucoma; MD: mean deviation; SEM: standard error of mean; ROC: receiver operating characteristic.