fig5

Figure 5. CDEVs function as an immunotherapy in tumors. (A) Data for the proportion of tumor-infiltrating CD8+ T cells; (B-D) Data for the proportion of GzmB, IFN-γ, and TNF-α secreted by tumor-infiltrating CD8+ T cells; (E) Data for the proportion of tumor-infiltrating CD4+ T cells; (F-H) Data for the proportion of GzmB, IFN-γ, and TNF-α secreted by tumor-infiltrating CD4+ T cells. Data are represented as mean ± SD. CDEVs: Celery-derived extracellular vesicles; PTX: paclitaxel; CDEVs-PTX: CDEVs loaded with PTX; PBS: phosphate buffer solution. (n = 4; ^*P < 0.05; ^**P < 0.01; ^***P < 0.01; ^***P < 0.001).