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![Electrochemical detection of extracellular vesicles for early diagnosis: a focus on disease biomarker analysis](https://image.oaes.cc/e371bceb-d798-4f4f-9336-2f063dff87a4/evcna3072.fig.1.jpg)
Figure 1. Electrochemical biosensor for detection of EVs-related protein biomarkers. (A) Electrochemical paper sandwich immunosensor: capture, quantification, and identification of generic and ovarian cancer cell-derived EVs[18]; (B) A sandwich-type electrochemical sensing platform for exosome enrichment and detection using Prussian blue/graphene oxide (PB/GO) and spiky Au@Fe3O4 nanoparticles[77]; (C) An integrated 8-channel magnetic-electrochemical exosome (iMEX) platform for profiling protein markers in EVs[78]; (D) A microfabricated device with gold electrodes for rapid and cost-effective multiplex analysis of EVs and microsomes[79].