fig2

Delivery of miR-214 via extracellular vesicles downregulates <i>Xbp1</i> expression and <InlineParagraph>pro-inflammatory</InlineParagraph> cytokine genes in macrophages

Figure 2. miR-214 is enriched in iEVs and can be transferred to BMDM. (A) Schematic representation depicting the biological material (iEVs) analyzed in B; (B) Bar graphs depicting: Ct values for SnoRNA202 and miR-214, and fold change in miR-214 in iEVs subject to miR-specific qPCR. Fold change was calculated relative to iEVs from untransfected J558L cells and normalized using SnoRNA202; (C) Schematic representation depicting the biological material (BMDM treated with iEVs) analyzed in D; (D) Bar graphs depicting Ct values and amplification plots for SnoRNA202 (upper) and miR-214 (lower) from BMDM treated with iEVs.

Extracellular Vesicles and Circulating Nucleic Acids
ISSN 2767-6641 (Online)
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