fig2
![Delivery of miR-214 via extracellular vesicles downregulates <i>Xbp1</i> expression and <InlineParagraph>pro-inflammatory</InlineParagraph> cytokine genes in macrophages](https://image.oaes.cc/6241f9a3-1de5-4229-b6c8-6c9e709cf2c3/evcna3064.fig.2.jpg)
Figure 2. miR-214 is enriched in iEVs and can be transferred to BMDM. (A) Schematic representation depicting the biological material (iEVs) analyzed in B; (B) Bar graphs depicting: Ct values for SnoRNA202 and miR-214, and fold change in miR-214 in iEVs subject to miR-specific qPCR. Fold change was calculated relative to iEVs from untransfected J558L cells and normalized using SnoRNA202; (C) Schematic representation depicting the biological material (BMDM treated with iEVs) analyzed in D; (D) Bar graphs depicting Ct values and amplification plots for SnoRNA202 (upper) and miR-214 (lower) from BMDM treated with iEVs.