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![NUPR1 packaged in extracellular vesicles promotes murine triple-negative breast cancer in a type 1 interferon-independent manner](https://image.oaes.cc/97161211-15ba-4a97-8ace-d75b81187793/evcna5059.fig.4.jpg)
Figure 4. Reserpine suppresses release of TEV from murine TNBC cell lines. (A) Quantification of total extracellular vesicle concentration from EO771 and 4T1 cell culture media after 24 h in vehicle or 10 µM reserpine; (B) Nanoparticle tracking analysis comparing size distribution and concentration of TEV from EO771 cell culture media after 24 h in vehicle or 10 µM reserpine; (C) Nanoparticle tracking analysis comparing size distribution and concentration of TEV from 4T1 cell culture media after 24 h in vehicle or 10 µM reserpine. Quantitative data are represented as mean ± SEM; P values: * P < 0.05; ** P < 0.01; *** P < 0.001 and ns for not significant from Student’s t test (panel A).