fig1

NUPR1 packaged in extracellular vesicles promotes murine triple-negative breast cancer in a type 1 interferon-independent manner

Figure 1. CH25H expression in Triple Negative Breast Cancer (TNBC) Primary Tumor. (A) Analysis of GSE58135 using GEO2R comparing CH25H expression between TNBC tissue and normal adjacent tissue (n = 42); (B) Schematic of EO771 intramammary (im) injection into wild-type (WT) and mice lacking CH25H (Ch25h-/-); (C) EO771 primary tumor growth following im injection overtime in WT and Ch25h-/- mice (n = 5); (D) Representative images of excised primary EO771 tumors. Quantitative data are represented as mean ± SEM; P values: * P < 0.05; ** P < 0.01; *** P < 0.001 from Anova test. WT: wild-type.

Extracellular Vesicles and Circulating Nucleic Acids
ISSN 2767-6641 (Online)
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