fig4
![Bioprinting extracellular vesicles as a](https://image.oaes.cc/d5347aac-9663-4282-8df0-c020e9bdd06a/5742.fig.4.jpg)
Figure 4. Bioprinted HUVECs-sEVs constructs promote angiogenesis (modified from [103]). (A) Schematic representation of the bioprinting process to manufacture EV-loaded scaffolds; (B) SEM images of 3D bioprinted GelMA with HUVECs-sEVs. Yellow arrows denote the EVs; (C) Bioprinted HUVECs-sEVs promote in vivo vessel formation after subcutaneous implantation in immunocompromised mice, with IB4-positive blood vessel structures. IB4, Isolectin B4; Normoxia EVs, EVs from normoxia HUVECs; hypoxia EVs, EVs from hypoxia HUVECs.