fig9

Figure 9. Schematic diagrams for the preparation and intramyocardial injection of IONP-NVs for cardiac repair. MSCs modified through the internalization of IONPs exhibited higher expression of therapeutic biomolecules. IONP-NVs were generated from IONP-MSCs by serial extrusion and contained contents similar to those of IONP-MSCs. Magnetic guidance following intramyocardial injection of IONP-NVs can improve cardiac retention of IONP-NVs. Reprinted with permission from[107].