fig3
![Engineered mammalian and bacterial extracellular vesicles as promising nanocarriers for targeted therapy](https://image.oaes.cc/241e8738-5ac8-4b1f-ad51-38ecc9978907/4777.fig.3.jpg)
Figure 3. (A) The procedure to produce hybrid nanoparticles by membrane fusion. Liposomes with targeting molecules on the surface can be delivered into EVs through membrane fusion[79]. Copyright 2018 WILEY-VCH. (B) The procedure to produce hybrid nanoparticles by membrane coating[80]. Copyright 2020 Ivyspring International Publisher. (C) The fusion of the targeting peptide with LAMP-2B[66]. Copyright 2021 Ivyspring International Publisher. (D) The fusion of the delivery molecule with CD63[81]. Copyright 2018 Springer Nature. (E) Targeted modification of EVs based on chemical covalent reactions[82]. Copyright 2021 Elsevier. (F) Targeted modification of EVs based on chemical non-covalent reactions[82]. Copyright 2021 Elsevier. LAMP-2B: Lysosome-associated membrane glycoprotein 2B.