fig4

Figure 4. Identification, validation and functional enrichment analysis of DEmis in SPEVs. (A) Volcano plot displaying the DEmis between the SPEVs of the H and L groups. (B) Top 20 biological processes (FDR < 0.05) enriched with mRNAs targeted by DEmis. (C) The top 20 KEGG pathways (FDR < 0.05) enriched with the target genes of DEmis are shown in the bubble diagram. (D) The expression levels of ten DEmis were validated by qPCR.