fig4

Figure 4. Hierarchical clustering of the loci differentially methylated in ischemia vs. control in the normal (left) and high-fat diet (right) reveals clusters where methylation was either increased (red) or decreased (green) in ischemia (3 samples in the middle) compared to control (3 samples on the left). These changes were nullified by EV treatment in some (brown rectangles) but not all (green rectangles) loci.