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![Pathogenesis and biomarkers in ANCA-associated vasculitis](https://image.oaes.cc/a35ce3d1-6a2a-4406-883b-9afddc31ef85/4195.fig.1.jpg)
Figure 1. The inflammation cascade of anti-neutrophil cytoplasmic antibody (ANCA)-antibody associated vasculitis. ANCAs produced by plasma cells bind to myeloperoxidase and proteinase 3 produced by activated neutrophils (mediated by factors such as TNF-α or