fig3

Figure 3. CTP parameters are derived from the measurement of the transit of iodinated contrast through the cerebral vessels and parenchyma. The arterial input function (AIF) and venous output function (VOF) underpin the mathematical calculation of these parameters. (A) A visual representation of the AIF (red line) and VOF (blue line) of an acute basilar artery occlusion 1 h after stroke onset. Mistar neuroperfusion package automatically selects (B) an artery from the anterior circulation for calculation of the AIF and (C) a venous sinus for calculation of the VOF.