fig5

Figure 5. In vivo electrophysiological analyses confirm human induced pluripotent stem cell derived cardiomyocyte (hiPSC-CM) electromechanical enhancement of the host myocardium. Voltage and activation mapping were performed using a custom-engineered software program. Asterisks indicate the approximate epicardial pacing location for activation mapping only. Boxes on the sham, chronic heart failure (CHF), and CHF + hiPSC-CM patch hearts denote tissue region mapped to generate color maps for voltage and activation mapping. The α, β, and δ denote the focal area of local electrocardiograms from each group with respect to voltage or activation maps^[16]. *Denotes the approximate location of pacing electrode.