fig3

From: Perspective on the development of a bioengineered patch to treat heart failure: rationale and proposed design of phase I clinical trial

Figure 3. Echocardiographic parameters-CHF rats treated with hiPSC-CM patch; Data are mean ± SE where *denotes significance (P < 0.05) vs. CHF, and **denotes significance (P < 0.05) vs. Sham. Sham: N = 12; CHF: N = 8-21, hiSPC-CM: N = 20-24 per group. CHF: Chronic heart failure; hiPSC-CM: human induced pluripotent stem cell derived cardiomyocytes, EF: ejection fraction; e’: early LV relaxation velocity; E/e’: ratio of early peak flow velocity to early peak LV velocity; e’/a’: ratio of early to late peak LV velocities; AWdia: anterior wall thickness in diastole; PWdia: posterior wall thickness in diastole^[16]; LV: left ventricular.