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![Perivascular mast cells promote neointimal elastin deposition and suppress chronic vein graft restenosis in hyperlipidaemic mice](https://image.oaes.cc/55fdf6e6-176c-4571-9232-1794d7d2713a/2068.fig.2.png)
Figure 2. Mast cell deficiency in hyperlipidaemic mice increased neointima area with elevated chronic cell proliferation. (A) Representative images of cell proliferation in 4-week-old vein grafts. Proliferating cells were labelled using an antibody against Ki67 (green) and cell nuclei by DAPI (blue). The neointimal area in apoE-/- KitW-sh/W-sh vein grafts was significantly higher than all other groups (B), associated with elevated cell proliferation by 4 weeks (C). n > 6 for all groups; **P < 0.01 by one-way analysis of variance plus Tukey post hoc test