fig2

Figure 2. Atherogenic effects of sialylated (hollow circles) and desialylated (filled circles) LDL density subfractions from type 1 (A) and type 2 (B) diabetic patients. Atherogenic effect was assessed as the ability of LDL (50 μg/mL) to induce significant increase in the cholesterol content of subendothelial cells cultured from normal human aortic intima. Intracellular cholesterol content is expressed as the percentage of cholesterol level in control cells. The rectangular shaded areas denote the range of statistically insignificant changes in intracellular cholesterol level. LDL: low-density lipoprotein