REFERENCES
1. Jenne CN, Urrutia R, Kubes P. Platelets: bridging hemostasis, inflammation, and immunity. Int J Lab Hematol 2013;35:254-261.
2. Reems JA, Pineault N, Sun S. In Vitro Megakaryocyte Production and Platelet Biogenesis: State of the Art. Transfus Med Rev 2010;24:33-43.
3. Italiano JE, Lecine P, Shivdasani RA, Hartwig JH. Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes. J Cell Biol 1999;147:1299-312.
4. Menter DG, Kopetz S, Hawk E, Sood AK, Loree JM, et al. Platelet “first responders” in wound response, cancer, and metastasis. Cancer Metastasis Rev 2017;36:199-213.
5. Zharikov S, Shiva S. Platelet mitochondrial function: from regulation of thrombosis to biomarker of disease. Biochem Soc Trans 2013;41:118-23.
6. Kanikarla-Marie P, Lam M, Sorokin AV, Overman MJ, Kopetz S, et al. Platelet Metabolism and Other Targeted Drugs; Potential Impact on Immunotherapy. Front Oncol 2018;8:107.
7. Guo X, Wu J, Du J, Ran J, Xu J. Platelets of type 2 diabetic patients are characterized by high ATP content and low mitochondrial membrane potential. Platelets 2009;20:588-93.
8. Avila C, Huang RJ, Stevens MV, Aponte AM, Tripodi D, et al. Platelet mitochondrial dysfunction is evident in type 2 diabetes in association with modifications of mitochondrial anti-oxidant stress proteins. Exp Clin Endocrinol Diabetes 2012;120:248-51.
9. Lenaz G, Bovina C, Castelluccio C, Fato R, Formiggini G, et al. Mitochondrial Complex I defects in aging. Mol Cell Biochem 1997;174:329-33.
10. Ajzenberg N, Haghighat Talab AT, Massé JM, Drouin A, Jondeau K, et al. Platelet shape change and subsequent glycoprotein redistribution in human stenosed arteries. Platelets 2005;16:13-8.
11. Verhoeven AJ, Mommersteeg ME, Akkerman JW. Quantification of energy consumption in platelets during thrombin-induced aggregation and secretion. Tight coupling between platelet responses and the increment in energy consumption. Biochem J 1984;221:777-87.
12. Verhoeven AJ, Mommersteeg ME, Akkerman JW. Comparative studies on the energetics of platelet responses induced by different agonists. Biochem J 1986;236:879-87.
13. Leoncini G, Maresca M, Colao C. Oxidative metabolism of human platelets. Biochem Int 1991;25:647-55.
14. Sjövall F, Ehinger JKH, Marelsson SE, Morota S, Frostner EA, et al. Mitochondrial respiration in human viable platelets--methodology and influence of gender, age and storage. Mitochondrion 2013;13:7-14.
15. Baracca A, Barogi S, Carelli V, Lenaz G, Solaini G. Catalytic activities of mitochondrial ATP synthase in patients with mitochondrial DNA T8993G mutation in the ATPase 6 gene encoding subunit a. J Biol Chem 2000;275:4177-82.
16. Kramer PA, Ravi S, Chacko B, Johnson MS, Darley-Usmar VM. A review of the mitochondrial and glycolytic metabolism in human platelets and leukocytes: implications for their use as bioenergetic biomarkers. Redox Biol 2014;2:206-10.
17. Garcia-Souza LF, Oliveira MF. Mitochondria: biological roles in platelet physiology and pathology. Int J Biochem Cell Biol 2014;50:156-60.
18. Ravera S, Signorello MG, Bartolucci M, Ferrando S, Manni L, et al. Extramitochondrial energy production in platelets. Biol Cell 2018;110:97-108.
19. Li Z, Delaney MK, O’Brien KA, Du X. Signaling During Platelet Adhesion and Activation. Arterioscler Thromb Vasc Biol 2010;30:2341-9.
20. Morelli AM, Ravera S, Calzia D, Panfoli I. Hypothesis of lipid-phase-continuity proton transfer for aerobic ATP synthesis. J Cereb Blood Flow Metab 2013;33:1838-42.
21. Morelli A, Ravera S, Calzia D, Panfoli I. An update of the chemiosmotic theory as suggested by possible proton currents inside the coupling membrane. Open Biol 2019;9:180221.
22. Panfoli I, Calzia D, Ravera S, Bruschi M, Tacchetti C, et al. Extramitochondrial tricarboxylic acid cycle in retinal rod outer segments. Biochimie 2011;93:1565-75.
23. Ravera S, Bartolucci M, Calzia D, Aluigi MG, Ramoino P, et al. Tricarboxylic acid cycle-sustained oxidative phosphorylation in isolated myelin vesicles. Biochimie 2013;95:1991-8.
24. Ravera S, Panfoli I, Calzia D, Aluigi MG, Bianchini P, et al. Evidence for aerobic ATP synthesis in isolated myelin vesicles. Int J Biochem Cell Biol 2009;41:1581-91.
25. Ravera S, Aluigi MG, Calzia D, Ramoino P, Morelli A, et al. Evidence for ectopic aerobic ATP production on C6 glioma cell plasma membrane. Cell Mol Neurobiol 2011;31:313-21.
26. Ravera S, Nobbio L, Visigalli D, Bartolucci M, Calzia D, et al. Oxydative phosphorylation in sciatic nerve myelin and its impairment in a model of dysmyelinating peripheral neuropathy. J Neurochem 2013;126:82-92.
27. Panfoli I, Ravera S, Bruschi M, Candiano G, Morelli A. Proteomics unravels the exportability of mitochondrial respiratory chains. Expert Rev Proteomics 2011;8:231-9.
28. Chang HY, Huang HC, Huang TC, Yang PC, Wang YC, et al. Ectopic ATP synthase blockade suppresses lung adenocarcinoma growth by activating the unfolded protein response. Cancer Res 2012;72:4696-706.
29. Arakaki N, Kita T, Shibata H, Higuti T. Cell-surface H+-ATP synthase as a potential molecular target for anti-obesity drugs. FEBS Lett 2007;581:3405-9.
30. Mangiullo R, Gnoni A, Leone A, Gnoni GV, Papa S, et al. Structural and functional characterization of F(o)F(1)-ATP synthase on the extracellular surface of rat hepatocytes. Biochim Biophys Acta 2008;1777:1326-35.
31. Cossu V, Marini C, Piccioli P, Rocchi A, Bruno S, et al. Obligatory role of endoplasmic reticulum in brain FDG uptake. Eur J Nucl Med Mol Imaging 2019;46:1184-96.
32. Marchi S, Patergnani S, Pinton P. The endoplasmic reticulum-mitochondria connection: one touch, multiple functions. Biochim Biophys Acta 2014;1837:461-9.
33. Pham-Huy LA, He H, Pham-Huy C. Free radicals, antioxidants in disease and health. Int J Biomed Sci 2008;4:89-96.
36. Genova ML, Baracca A, Biondi A, Casalena G, Faccioli M, et al. Is supercomplex organization of the respiratory chain required for optimal electron transfer activity? Biochim Biophys Acta 2008;1777:740-6.
37. Ravera S, Bartolucci M, Cuccarolo P, Litamè E, Illarcio M, et al. Oxidative stress in myelin sheath: The other face of the extramitochondrial oxidative phosphorylation ability. Free Radic Res 2015;49:1-36.
38. Calzia D, Degan P, Caicci F, Bruschi M, Manni L, et al. Modulation of the rod outer segment aerobic metabolism diminishes the production of radicals due to light absorption. Free Radic Biol Med 2019;136:183.
39. Bartimoccia S, Nocella C, Pastori D, Pignatelli P, Carnevale R. Platelet Oxidative Stress and Antioxidant Nutrients. J Vasc Med Surg 2014;02:1-4.
41. Scalbert A, Manach C, Morand C, Rémésy C, Jiménez L. Dietary polyphenols and the prevention of diseases. Crit Rev Food Sci Nutr 2005;45:287-306.
42. Pérez-Torres I, Guarner-Lans V, Rubio-Ruiz ME. Reductive Stress in Inflammation-Associated Diseases and the Pro-Oxidant Effect of Antioxidant Agents. Int J Mol Sci 2017;18:E2098.
43. Sobotková A, Másová-Chrastinová L, Suttnar J, Stikarová J, Májek P, et al. Antioxidants change platelet responses to various stimulating events. Free Radic Biol Med 2009;47:1707-14.
44. Liu M, Wallmon A, Olsson-Mortlock C, Wallin R, Saldeen T. Mixed tocopherols inhibit platelet aggregation in humans: potential mechanisms. Am J Clin Nutr 2003;77:700-6.
45. Petroni A, Blasevich M, Salami M, Papini N, Montedoro GF, et al. Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil. Thromb Res 1995;78:151-60.
46. Pacchiarini L, Tua A, Grignani G. In vitro effect of reduced glutathione on platelet function. Haematologica 1996;81:497-502.
47. Sagesaka-Mitane Y, Miwa M, Okada S. Platelet aggregation inhibitors in hot water extract of green tea. Chem Pharm Bull (Tokyo) 1990;38:790-3.
48. Assefa AD, Ko EY, Moon SH, Keum YS. Antioxidant and antiplatelet activities of flavonoid-rich fractions of three citrus fruits from Korea. 3 Biotech 2016;6:109.
