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![Resection of orthotopic murine brain glioma](https://image.oaes.cc/08b922fa-6ebd-4004-a8d9-70294cb495a9/3646.fig.1.jpg)
Figure 1. Performance of craniotomy. Four burr holes (white holes) were placed with a hand-held Jacob’s chuck. A craniotomy was then performed by cutting into the skull with micro-scissors and connecting the small burr holes with the base of the flap positioned medially (dashed line)