fig1

Postnatal toxicant exposure in 3xTgAD mice promotes gene x environment-related early alterations to neuroimmune epigenetic profiles

Figure 1. Quantification of hippocampal DAP12+ expression by sex over time in untreated WT (A) and 3xTgAD (B) mice. Representative images of hippocampal DAP12+ expression at PND10, 15, and 21 for females and males in WT (C) and 3xTgAD (D) hippocampus. Data expressed as mean % of sex- and strain-matched PND10 controls ± SEM. n = 3 mice/sex/age/strain. scale bar = 26 mm. Statistically significant at P < 0.05 (*-by age) (#-by sex), *P < 0.01 interaction (age*sex). PND: postnatal day; WT: wildtype; ctl: control

Neuroimmunology and Neuroinflammation
ISSN 2349-6142 (Online) 2347-8659 (Print)

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