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![CAR-T cell therapy in neuro-oncology: applications and toxicity](https://image.oaes.cc/7e5b3295-869e-4484-9beb-1b873a4d7f3e/2852.fig.1.png)
Figure 1. Multifocal glioblastoma responding to intraventricular delivery of IL13Ra2-redirected CAR T-cell therapy (modified from Brown et al.[28], permission for use granted by NEJM). A: sagittal view of gadolinium-enhanced MRI (top row) and FDG-PET (bottom row) images showing tumor regression of tumors 6 and 7 in the brain (yellow arrowheads and circles); B: sagittal gadolinium-enhanced MRI (top row) and coronal DG-PET (bottom row) images exhibiting tumor regression of tumor 8 in the spine (yellow circles)