fig1
![<i>In silico</i> design of novel gold-phosphate containing compounds as selective inhibitors of cathepsin B in neuroinflammation](https://image.oaes.cc/cff6e8e7-6581-4595-8e0a-779cbd924b5e/2758.fig.1.png)
Figure 1. A schematic representation of the mutual orientation and disposition of P-CF3 part of triethylphosphine and C-alpha (CA) atom of the Cys29 residue of cathepsin B (A). Active site of cathepsin В with the CF3 group (F atoms are colored green) (B). Cys29 is replaced with Ala29 (the surface of Cys29 is shown in mesh)