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![Photodynamic therapy mediated immune therapy of brain tumors](https://image.oaes.cc/547b1532-9e38-4bdb-a4aa-ffd81ebb388f/2671.fig.3.png)
Figure 3. In vivo generated PDT-APC vaccine. (1) Intra-cranial inoculation of glioma cells; (2) tumor development, PS injection into the animal; (3) APC (DC/Ma) precursors obtained from donor animal, cultured alone in vitro resulting in naïve APC; (4) iPDT of tumor in situ; (5) immunization with naive APC injection directly into PDT treated tumor. APC: antigen presenting cell; PDT: photodynamic therapy; PS: photosensitizer