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![Photodynamic therapy mediated immune therapy of brain tumors](https://image.oaes.cc/547b1532-9e38-4bdb-a4aa-ffd81ebb388f/2671.fig.1.png)
Figure 1. Mechanism and targets for photodynamic therapy. Following photosensitizer administration, light of a particular wavelength matching an absorption resonance of the photosensitizer, is used to excite the molecule up to a triple state. The excited photosensitizer transfers energy to ground state molecular oxygen (3O2) resulting in the generation of singlet molecular oxygen (1O2), a potent reactive oxygen species, resulting in cell death. cell membrane (CM) mitochondria (Mito), endosome, lysosome (Lyso), and endoplasmic reticulum (ER)