fig1

Figure 1. Mechanism and targets for photodynamic therapy. Following photosensitizer administration, light of a particular wavelength matching an absorption resonance of the photosensitizer, is used to excite the molecule up to a triple state. The excited photosensitizer transfers energy to ground state molecular oxygen (³O₂) resulting in the generation of singlet molecular oxygen (¹O₂), a potent reactive oxygen species, resulting in cell death. cell membrane (CM) mitochondria (Mito), endosome, lysosome (Lyso), and endoplasmic reticulum (ER)