fig5

Figure 5. Minocycline treatment reduces the number of cells undergoing apoptotic cell death. Tunel positive cells were counted in sections from vehicle and minocycline treated mice harvested at 2 and 5 days post SCI. Cell death was evident 2 days after injury and was still ongoing at 5 days. The number of Tunel positive cells counted from the minocycline group was significantly lower than the vehicle group at 5 days post SCI (Student's t-test, *P < 0.05, n = 9/group, one longitudinal section containing the central canal per mouse). SCI: spinal cord injury