fig1

Differentiation of radiation necrosis from glioblastoma recurrence after radiotherapy

Figure 1. T2-W axial images (a), T1-W axial images with intravenous contrast administration (b), demonstrated an extensive edematous lesion with mass effect and heterogeneous enhancement (arrows), characteristic of both tumor recurrence and radiation necrosis. The diffusion weighted imaging (DWI) demonstrated decreased values of the apparent diffusion coefficient (ADC) maps (c) (1.2-1.8x10¯³mm²) consisted with malignant tumor infiltration. However, the fractional anisotropy (FA) (d) maps showed increased white matter tracts destruction (low FA) and the perfusion maps (CBV) (e) depicted very low perfusion, both consisted with radiation-induced necrosis. SPECT (f) revealed increased metabolic activity (arrowheads) consisted with tumor recurrence

Neuroimmunology and Neuroinflammation
ISSN 2349-6142 (Online) 2347-8659 (Print)

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