fig9

Figure 9. Treatment of amyloid precursor protein (APP) mice with chlorpyrifos oxon (CPO) results in a decrease in neurotrophic factors. Brain nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 levels (panels a, b and c, respectively) were determined by enzyme-linked immunosorbent assay in APP mice (control) and APP mice treated with CPO (CPO). Values are shown as the mean ± standard error of the mean, and n = 12. *Statistically significant (P < 0.05)