Topic: Bacterial Membrane Vesicles in Pathogen-Host Interaction and Vaccine Development

Shedding of bacterial membrane vesicles (bMVs) constitutes a universal mechanism for inter-kingdom and intra-kingdom communication that is conserved among prokaryotic and eukaryotic microbes. Exploring the interaction mechanisms between pathogen and host mediated by bMVs is expected to open a new world for the treatment of infectious diseases.

The bacterial membrane vesicles (bMVs), as a naturally secreted nanoscale vesicular structure, encapsulate the bacterial outer membrane and other components, and are prone to genetically engineering, making them widely used in fields such as pathogen-host interaction, vaccine development, and delivery vector design for cancer therapy.

This special issue aims to contribute original articles and reviews covering but not limited to the following topics:

1. Investigate the regulatory mechanisms of bMVs mediated interactions between prokaryotes and eukaryotes;

2. Investigation of bMVs for the interaction mechanisms between pathogen and host via encapsulating nucleic acid molecules (small non-coding RNA et al) and other regulatory molecules;

3. Engineered bMVs as targeted delivery vector for cancer therapy;

4. Development of engineered or wild-type bMVs-based vaccines against infectious diseases.