fig2
![Targeting facial aging with nano and regenerative technologies and procedures](https://image.oaes.cc/abbfd26c-6cf7-4ba8-be28-11a2134cc9e2/3320.fig.2.jpg)
Figure 2. Crows feet skin wrinkles before and after daily application of nano-collagen for 3 weeks (Marine Collagen Biologicals, Inc., San Diego, CA). Results were less spectacular in other cases, however, perhaps due to different individual nuclear gene expression profiles and skin biology[16]